Patricia Clarkson

Mia

Rosario Dawson

Lili

Lyndsy Fonseca

Cheyanne

Ginnifer Goodwin

Charlotte

Jeanne Tripplehorn

Pearl

Emily Skinner

Sally

Carla Gallo

Laura

Aisha Hinds

Bernice

Josh Holloway

Bill

Jennifer Morrison

Sheila

Austin Nichols

Edward

Annie Potts

Helen

Xander Berkeley

Peter

Kathy Najimy

Rocky

Romy Rosemont

Lynne

Tony Shalhoub

Mitch

Jenifer Lewis

Maggie

Tracee Ellis Ross

Alyssa

Jeffrey Tambor

Danny

David Eigenberg

Lenny

Taylor Kinney

Tommy

Bob Newhart

Dr. Roth

Ravi Patel

Dr. Desai

Alan Ruck

Sam Jarente

Scott Wilson

Bill (Older)

Kirk Baily

Scott

Israel Sáez de Miguel

Dimitri

Ava Acres

Pearl at age 7

Josh Dallas

Henry

Harmon Jones

Ben