Sylvia Sidney

Jennie Gerhardt

Donald Cook

Lester Kane

Mary Astor

Letty Pace

Edward Arnold

Sen. Brander

H.B. Warner

William Gerhardt

Theodore von Eltz

Robert Kane

Dorothy Libaire

Louise Kane

Louise Carter

Mrs. Gerhardt

Jane Darwell

Boardinghouse Keeper (uncredited)

Frank Reicher

Old Weaver (uncredited)

Betsy Ann Hisle

Veronica Gerhardt (uncredited)

Edward LeSaint

Lester's Doctor (uncredited)

Morgan Wallace

O'Brien (uncredited)

Cora Sue Collins

Vesta at Age 6