Chevy Chase

Clark Griswold

Beverly D'Angelo

Ellen Griswold

Randy Quaid

Cousin Eddie

Ethan Embry

Russell 'Rusty' Griswold

Marisol Nichols

Audrey Griswold

Miriam Flynn

Cousin Catherine

Shae D'Lyn

Cousin Vicki

Wayne Newton

Himself

Siegfried Fischbacher

Siegfried

Roy Horn

Roy

Wallace Shawn

Marty

Sid Caesar

Mr Ellis

Julio Oscar Mechoso

Limo Driver

Sly Smith

Mirage Security Guard

Julia Sweeney

Mirage Reception Person

Corinna Harney

Girl at Blackjack Table

Joe Armeno

Roulette Stickman

Christie Brinkley

Woman in Ferrari

Juliette Brewer

Cousin Ruby Sue

Zachariah Moyes

Cousin Denny

John Finnegan

Hoover Dam Guide

Howard Platt

Maitre'd

Maria Cina

Mirage Cashier

Wendy Kaufman

Wendy

Joe Lacoco

Riviera Bartender

C.C. Costigan

Kelli

Shannah Laumeister Stern

Mariah

Bud Ekins

O'Shea's Security Guard

Gary Devaney

Croupier #2

Jerry Weintraub

Jilly

S.A. Griffin

Pit Boss

Lou DiMaggio

Casino Host

Ruth Gillis

Saleswoman

Jason Stuart

Buffet Guy

Frank Washko Jr.

Guess Which Hand Dealer

Clinton Brandhagen

Valet

Hayley Mortison

Girl in Hot Tub

Rusty Meyers

Club Manager

Billy Morrissette

Paramedic #1

Sharon Mendel

Paramedic #2

Larry Hankin

Preacher

Alana Austin

Tourist (uncredited)

Vanessa Bednar

Hot Pool Model (uncredited)

JoAnn Bush

Flight Attendant (uncredited)

Jeffrey Donovan

Hotel Employee (uncredited)

Billie Perkins

Casino Guest (uncredited)